Development and validation of a disulfidptosis-related scoring system to predict clinical outcome and immunotherapy response in acute myeloid leukemia by integrated analysis of single-cell and bulk RNA-sequencing

• Main Authors: Fangmin Zhong (Author), Junyao Jiang (Author), Fang-Yi Yao (Author), Jing Liu (Author), Xu Shuai (Author), Xin-Lu Wang (Author), Bo Huang (Author), Xiaozhong Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Disulfidptosis is a metabolically relevant mode of cell death, and its relationship with acute myeloid leukemia (AML) has not been clarified. In this study, disulfidptosis scores were computed to examine the potential biological mechanisms.Methods: Consensus clustering was applied to det...