Effect of Nilvadipine on the Cerebral Ischemia-Induced Impairment of Spatial Memory and Hippocampal Apoptosis in Rats

• Main Authors: Katsunori Iwasaki (Author), Kenichi Mishima (Author), Nobuaki Egashira (Author), Izzettin Hatip Al-khatib (Author), Daisuke Ishibashi (Author), Keiichi Irie (Author), Hirotoshi Kobayashi (Author), Takashi Egawa (Author), Michihiro Fujiwara (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: We investigated the effects of nilvadipine and amlodipine on the cerebral ischemia-induced impairment of spatial memory in 8-arm radial maze performance and hippocampal CA1 apoptosis in rats. Single cerebral ischemia impaired memory without inducing apoptosis. In these rats, neither nilvad...