Recombinant human milk fat globule-EGF factor VIII (rhMFG-E8) as a therapy for sepsis after acute exposure to alcohol

• Egile Nagusiak: Wayne W. Chaung (Egilea), Max Brenner (Egilea), Hao-Ting Yen (Egilea), Mahendar L. Ochani (Egilea), Asha Jacob (Egilea), Ping Wang (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2019-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Alcohol intake predisposes to infections and sepsis. Alcohol and sepsis inhibit the expression of milk fat globule epidermal growth factor-factor VIII (MFG-E8), a glycoprotein essential for optimal efferocytosis, resulting in the release of proinflammatory molecules and increased...