Intravenous route to choroidal neovascularization by macrophage-disguised nanocarriers for mTOR modulation

• Main Authors: Weiyi Xia (Author), Chao Li (Author), Qinjun Chen (Author), Jiancheng Huang (Author), Zhenhao Zhao (Author), Peixin Liu (Author), Kai Xu (Author), Lei Li (Author), Fangyuan Hu (Author), Shujie Zhang (Author), Tao Sun (Author), Chen Jiang (Author), Chen Zhao (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Retinal pigment epithelial (RPE) is primarily impaired in age-related macular degeneration (AMD), leading to progressive loss of photoreceptors and sometimes choroidal neovascularization (CNV). mTOR has been proposed as a promising therapeutic target, while the usage of its specific inhibitor, rapam...