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LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson's Disease Mouse Model

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No treatments exist to slow or halt Parkinson's disease (PD) progression; however, inhibition of leucine-rich repeat kinase 2 (LRRK2) activity represents one of the most promising therapeutic strategies. Genetic ablation and pharmacological LRRK2 inhibition have demonstrated promise in blocking...

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Main Authors: Hien Tran Zhao (Author), Neena John (Author), Vedad Delic (Author), Karli Ikeda-Lee (Author), Aneeza Kim (Author), Andreas Weihofen (Author), Eric E. Swayze (Author), Holly B. Kordasiewicz (Author), Andrew B. West (Author), Laura A. Volpicelli-Daley (Author)
Format: Book
Published: Elsevier, 2017-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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