Perioperative sleep deprivation activates the paraventricular thalamic nucleus resulting in persistent postoperative incisional pain in mice

• Main Authors: Lei Li (Author), Huijie Zhang (Author), Zhenli Zheng (Author), Nan Ma (Author), Yidan Zhang (Author), Yaping Liu (Author), Jingjing Zhang (Author), Songxue Su (Author), Weidong Zang (Author), Jinping Shao (Author), Jing Cao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundThe duration of postsurgical pain is closely correlated with perioperative stress. Most patients suffer short-term sleep disorder/deprivation before and/or after surgery, which leads to extended postsurgical pain by an undetermined mechanism. The paraventricular thalamus (PVT) is a critica...