Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel.

• 主要な著者: Ravi S Kasinathan (著者), Lalit Kumar Sharma (著者), Charles Cunningham (著者), Thomas R Webb (著者), Robert M Greenberg (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and controlling schistosomiasis, a major limitation of...