Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel.

Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and controlling schistosomiasis, a major limitation of...

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Main Authors: Ravi S Kasinathan (Author), Lalit Kumar Sharma (Author), Charles Cunningham (Author), Thomas R Webb (Author), Robert M Greenberg (Author)
Format: Book
Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available