Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel.

• मुख्य लेखकों: Ravi S Kasinathan (लेखक), Lalit Kumar Sharma (लेखक), Charles Cunningham (लेखक), Thomas R Webb (लेखक), Robert M Greenberg (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and controlling schistosomiasis, a major limitation of...