Stability of 25 mg/mL Azacitidine Suspensions Kept in Fridge after Freezing

• Main Authors: Balouzet Clara (Author), Chanat Cédric (Author), Jobard Marion (Author), Brandely-Piat (Author), Chast François (Author)
• 格式: 图书
• 出版: De Gruyter, 2017-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Azacitidine is supplied as lyophilized powder to be reconstituted with sterile water for injection. The molecule is very unstable in aqueous medium (temperature-dependent process). Advance preparation and leftover management are made difficult by such poor stability. This study evaluates the stabili...