Vitamin E and Silymarin Reduce Oxidative Tissue Damage during Gentamycin-Induced Nephrotoxicity

• Main Authors: Tsvetelin Georgiev (Author), Galina Nikolova (Author), Viktoriya Dyakova (Author), Yanka Karamalakova (Author), Ekaterina Georgieva (Author), Julian Ananiev (Author), Veselin Ivanov (Author), Petya Hadzhibozheva (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aminoglycoside antibiotics and gentamicin (GN), in particular, are still widely used in clinical practice. It is a well-known fact that GN causes nephrotoxicity, and redox disturbances are discussed as a factor in its side effects. Recently, a new type of cell oxidative death, named ferroptosis, was...