FBXL16: a new regulator of neuroinflammation and cognition in Alzheimer's disease through the ubiquitination-dependent degradation of amyloid precursor protein

• मुख्य लेखकों: Liqun Qu (लेखक), Yong Tang (लेखक), Jianhui Wu (लेखक), Xiaoyun Yun (लेखक), Hang Hong Lo (लेखक), Linlin Song (लेखक), Xingxia Wang (लेखक), Huimiao Wang (लेखक), Ruilong Zhang (लेखक), Menghan Liu (लेखक), Cairen Wang (लेखक), Jerome P. L. Ng (लेखक), Xianjun Fu (लेखक), Io Nam Wong (लेखक), Vincent Kam Wai Wong (लेखक), Betty Yuen Kwan Law (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Activating the ubiquitin-proteasome system to dismantle disease- related proteins such as tau, β-amyloid, APP, and α-synuclein is an important focus in the research of neurodegenerative proteinopathy. By analyzing the serum RNA extracted from wild-type and Alzheimer's diseas...