Priming of innate antimycobacterial immunity by heat-killed Listeria monocytogenes induces sterilizing response in the adult zebrafish tuberculosis model

• Main Authors: Hanna Luukinen (Author), Milka Marjut Hammarén (Author), Leena-Maija (Author), Aleksandra Svorjova (Author), Laura Kantanen (Author), Sampsa Järvinen (Author), Bruno Vincent Luukinen (Author), Eric Dufour (Author), Mika Rämet (Author), Vesa Pekka Hytönen (Author), Mataleena Parikka (Author)
• Format: Book
• Published: The Company of Biologists, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium tuberculosis remains one of the most problematic infectious agents, owing to its highly developed mechanisms to evade host immune responses combined with the increasing emergence of antibiotic resistance. Host-directed therapies aiming to optimize immune responses to improve bacterial...