Modulation of Circadian Rhythm of DNA Synthesis in Tumor Cells by Inhibiting Platelet-Derived Growth Factor Signaling

• Main Authors: Hiroo Nakagawa (Author), Satoru Koyanagi (Author), Yukako Kuramoto (Author), Akiko Yoshizumi (Author), Naoya Matsunaga (Author), Hiroshi Shimeno (Author), Shinji Soeda (Author), Shigehiro Ohdo (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Circadian synchronization of cell proliferation is observed not only in normal healthy tissues but also in malignant solid tumors. However, the proliferation rhythm of tumor cells is often different from that of normal cells. We reported here that the peculiar rhythm of tumor cell proliferation was...