L-Serine-Modified Poly-L-Lysine as a Biodegradable Kidney-Targeted Drug Carrier for the Efficient Radionuclide Therapy of Renal Cell Carcinoma

• Main Authors: Hidemasa Katsumi (Author), Sho Kitada (Author), Shintaro Yasuoka (Author), Rie Takashima (Author), Tomoki Imanishi (Author), Rina Tanaka (Author), Satoru Matsuura (Author), Hiroyuki Kimura (Author), Hidekazu Kawashima (Author), Masaki Morishita (Author), Akira Yamamoto (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, L-serine (Ser)-modified poly-L-lysine (PLL) was synthesized to develop a biodegradable, kidney-targeted drug carrier for efficient radionuclide therapy in renal cell carcinoma (RCC). Ser-PLL was labeled with ¹¹¹In/⁹⁰Y via diethylene...