Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy

• Main Authors: Yimiao Sang (Author), Xiaohong Gu (Author), Lulu Pan (Author), Chunxiang Zhang (Author), Xing Rong (Author), Tingting Wu (Author), Tianhe Xia (Author), Yuechun Li (Author), Lisha Ge (Author), Yuanhai Zhang (Author), Maoping Chu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current therapeutics options for viral myocarditis are unsatisfactory. Melatonin (MLT), a hormone secreted by the pineal gland and other organs, has protective effects on ischemic heart injury. However, the potential therapeutic effect of MLT on viral myocarditis is unknown. In this study, we invest...