Etanercept Ameliorates Cardiac Fibrosis in Rats with Diet-Induced Obesity

• Main Authors: Chia-Chen Hsu (Author), Yingxiao Li (Author), Chao-Tien Hsu (Author), Juei-Tang Cheng (Author), Mang-Hung Lin (Author), Kai-Chun Cheng (Author), Shang-Wen Chen (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diet-induced obesity (DIO) is considered the main risk factor for cardiovascular diseases. Increases in the plasma levels of tumor necrosis factor alpha (TNF-α) is associated with DIO. Etanercept, a TNF-α inhibitor, has been shown to alleviate cardiac hypertrophy. To investigate the effect of etaner...