Opposite Expression of Hepatic and Pulmonary Corticosteroid-Binding Globulin in Cystic Fibrosis Patients

• Main Authors: Anastasia Tchoukaev (Author), Jessica Taytard (Author), Nathalie Rousselet (Author), Carine Rebeyrol (Author), Dominique Debray (Author), Sabine Blouquit-Laye (Author), Marie-Pierre Moisan (Author), Aline Foury (Author), Loic Guillot (Author), Harriet Corvol (Author), Olivier Tabary (Author), Philippe Le Rouzic (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is characterized by a chronic pulmonary inflammation. In CF, glucocorticoids (GC) are widely used, but their efficacy and benefit/risk ratio are still debated. In plasma, corticosteroid-binding globulin (CBG) binds 90% of GC and delivers them to the inflammatory site. The main g...