Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening

• Main Authors: Wei Liao (Author), Wanren Yang (Author), Jiecheng Xu (Author), Zhengming Yan (Author), Mingxin Pan (Author), Xiaoping Xu (Author), Shuqin Zhou (Author), Yu Zhu (Author), Jianqiang Lan (Author), Min Zeng (Author), Xu Han (Author), Shao Li (Author), Yang Li (Author), Kangyan Liang (Author), Yi Gao (Author), Qing Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Cancer is the second leading cause of death globally. However, most of the new anti-cancer agents screened by traditional drug screening methods fail in the clinic because of lack of efficacy. Choosing an appropriate in vitro tumor model is crucial for preclinical drug screening. In this...