Janus Kinase inhibitors in dermatology: a review

• Main Authors: Bárbara Vieira-Granja (Author), Sofia Magina (Author)
• Formato: Livro
• Publicado em: Sociedade Portuguesa de Dermatologia e Venereologia, 2023-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Janus Kinases (JAKs) are a subset of cytoplasmic protein tyrosine kinases (TYK), crucial for the initiation of signaling pathways activated by cytokines through phosphorylation and activation of the signal transducer and activator of transcription (STAT) proteins. Selective JAK inhibitors can simult...