NEDD9 Facilitates Hypoxia-Induced Gastric Cancer Cell Migration via MICAL1 Related Rac1 Activation

• Main Authors: Shuo Zhao (Author), Pengxiang Min (Author), Lei Liu (Author), Lin Zhang (Author), Yujie Zhang (Author), Yueyuan Wang (Author), Xuyang Zhao (Author), Yadong Ma (Author), Hui Xie (Author), Chenchen Zhu (Author), Haonan Jiang (Author), Jun Du (Author), Luo Gu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims and Hypothesis: NEDD9 is highly expressed in gastric cancer and has a significant involvement in its pathogenesis. However, the mechanism behind hypoxia-promoted cancer cell migration and its regulation because of NEDD9 is still unknown. The aim of this study is to investigate the involvement o...