New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile

• Main Authors: Ioana-Mirela Vasincu (Author), Maria Apotrosoaei (Author), Sandra Constantin (Author), Maria Butnaru (Author), Liliana Vereștiuc (Author), Cătălina-Elena Lupușoru (Author), Frederic Buron (Author), Sylvain Routier (Author), Dan Lupașcu (Author), Roxana-Georgiana Taușer (Author), Lenuța Profire (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Aryl-propionic acid derivatives with ibuprofen as representative drug are very important for therapy, being recommended especially for anti-inflammatory and analgesic effects. On other hand 1,3-thiazolidine-4-one scaffold is an important heterocycle, which is associated with diff...