Evaluation of commonly used cardiovascular drugs in inhibiting vonoprazan metabolism in vitro and in vivo

• Main Authors: Yiran Wang (Author), Jihua Shi (Author), Dapeng Dai (Author), Jianping Cai (Author), Shuanghu Wang (Author), Yun Hong (Author), Shan Zhou (Author), Fangling Zhao (Author), Quan Zhou (Author), Peiwu Geng (Author), Yunfang Zhou (Author), Xue Xu (Author), Qingfeng Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As a novel acid-suppressing drug, vonoprazan shows the potential to replace traditional proton-pump inhibitors. With its widespread use, some adverse effects that require further study have emerged due to drug-drug interactions. Our study is the first experiment that evaluated the drug-drug interact...