Berberine Inhibits FOXM1 Dependent Transcriptional Regulation of POLE2 and Interferes With the Survival of Lung Adenocarcinoma

• Autors principals: Lulu Ni (Autor), Ping Sun (Autor), Xiaochun Fan (Autor), Zhongjie Li (Autor), Hongli Ren (Autor), Jiangan Li (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Background: Berberine is one of the most interesting and promising natural anticancer drugs. POLE2 is involved in many cellular functions such as DNA replication and is highly expressed in a variety of cancers. However, the specific molecular mechanism of berberine interfering with POLE2 expression...