Both IL-1β and TNF-α Regulate NGAL Expression in Polymorphonuclear Granulocytes of Chronic Hemodialysis Patients

• Main Authors: Adriana Arena (Author), Giovanna Stassi (Author), Daniela Iannello (Author), Domenica Gazzara (Author), Maria Calapai (Author), Carlo Bisignano (Author), Davide Bolignano (Author), Antonio Lacquaniti (Author), Michele Buemi (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. NGAL is involved in modulation of the inflammatory response and is found in the sera of uremic patients. We investigated whether hemodiafiltration (HDF) could influence the ability of polymorphonuclear granulocytes (PMGs) to release NGAL. The involvement of interleukin- (IL-)1β and tumor...