The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial

• Main Authors: Zhong-Ping Gou (Author), Yun-Li Zhao (Author), Lin-Ling Zou (Author), Ying Wang (Author), Shi-Qing Shu (Author), Xiao-Hong Zhu (Author), Li Zheng (Author), Qi Shen (Author), Zhu Luo (Author), Jia Miao (Author), Yong-Sheng Wang (Author), Xiao-Dong Luo (Author), Ping Feng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Capsule of alkaloids from the leaf of Alstonia scholaris (L.) R.Br. (Apocynaceae) (CALAS) is a new investigational botanical drug (No. 2011L01436) for bronchitis, post-infectious cough and asthma. Objective To observe the clinical safety and tolerability of CALAS. Materials and methods Subje...