Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model

• 主要な著者: Tomoki Kamatani (著者), Ryo Otsuka (著者), Tomoki Murata (著者), Haruka Wada (著者), Takeshi Takahashi (著者), Akihiro Mori (著者), Soichiro Murata (著者), Hideki Taniguchi (著者), Ken-ichiro Seino (著者)
• フォーマット: 図書
• 出版事項: BMC, 2022-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Off-the-shelf major histocompatibility complex (MHC)-matched iPS cells (iPSC) can potentially initiate host immune responses because of the existence of numerous minor antigens. To suppress allo-immune responses, combination of immunosuppressants is usually used, but its efficacy...