Gastroretentive raft liquid delivery system as a new approach to release extension for carrier-mediated drug

• 主要な著者: Samar M. Abouelatta (著者), Ahmed A. Aboelwafa (著者), Omaima N. El-Gazayerly (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Gabapentin (GBP), an antiepileptic and anti-neuropathic agent, suffers from short half-life (5-7 h), has narrow absorption window, and is absorbed via carrier-mediated mechanism resulting in frequent dosing, poor compliance, and poor bioavailability (<60%). Moreover, GBP is a freely water-soluble...