Icariside II Exerts Anti-Type 2 Diabetic Effect by Targeting PPARα/γ: Involvement of ROS/NF-κB/IRS1 Signaling Pathway

• Main Authors: Yiqi Li (Author), Yeli Li (Author), Nana Chen (Author), Linying Feng (Author), Jianmei Gao (Author), Nan Zeng (Author), Zhixu He (Author), Qihai Gong (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type 2 diabetes mellitus (T2DM) is a multisystem and complex metabolic disorder which is associated with insulin resistance and impairments of pancreatic β-cells. Previous studies have shown that icariside II (ICS II), one of the main active ingredients of <i>Herba Epimedii</i>, exerts p...