Release of prostaglandin D2 by murine mast cells: importance of metabolite formation for antiproliferative activity

• Hauptverfasser: C. Haberl (Verfasst von), L. Hültner (Verfasst von), A. Flügel (Verfasst von), M. Falk (Verfasst von), S. Geuenich (Verfasst von), W. Wilmanns (Verfasst von), C. Denzlinger (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 1998-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Prostaglandin (PG) D2 , PGJ2 and Δ12 -PGJ2 are antiproliferative eicosanoids. We investigated the production of PGD2 by murine bone marrow-derived mast cells (BMMC) taking into consideration metabolism of PGD2 to PGD2 and Δ12-PGJ2. PG-metabolites were quantified by high performance liquid chromatogr...