Angiopoietin-like 4 based therapeutics for proteinuria and kidney disease

• Autori principali: Sumant Singh Chugh (Autore), Camille eMace (Autore), Lionel C Clement (Autore), Maria eDel Nogal Avila (Autore), Caroline eMarshall (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2014-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Current drugs used to treat proteinuric disorders of the kidney have been borrowed from other branches of medicine, and are only partially effective. The discovery of a central, mechanistic role played by two different forms of the secreted glycoprotein Angiopoietin-like 4 (Angptl4) in human and exp...