RP-HPLC method development and validation for the quantification of Efonidipine hydrochloride in HME processed solid dispersions

Abstract Background Efonidipine hydrochloride (EFO) is a poorly water-soluble drug and, hence, has poor bioavailability. Solid dispersions (SDs) of EFO using Eudragit EPO were prepared using hot-melt extrusion (HME) for the first time. The current study aims at developing a simple RP-HPLC method to...

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Main Authors: Ashish S. Rajput (Author), Durgesh K. Jha (Author), Sharda Gurram (Author), Devanshi S. Shah (Author), Purnima D. Amin (Author)
Format: Book
Published: SpringerOpen, 2020-10-01T00:00:00Z.
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