RP-HPLC method development and validation for the quantification of Efonidipine hydrochloride in HME processed solid dispersions
Abstract Background Efonidipine hydrochloride (EFO) is a poorly water-soluble drug and, hence, has poor bioavailability. Solid dispersions (SDs) of EFO using Eudragit EPO were prepared using hot-melt extrusion (HME) for the first time. The current study aims at developing a simple RP-HPLC method to...
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Format: | Book |
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SpringerOpen,
2020-10-01T00:00:00Z.
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A1234.567 |
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