NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin

• Main Authors: Qian Zeng (Author), Bin-bin Wen (Author), Xin Liu (Author), Yong-yu Luo (Author), Zhen-gang Hu (Author), Lei Huang (Author), Xiao-hua Zhang (Author), Xiao-ting Huang (Author), Ting-ting Zhou (Author), Xiao-xue Sang (Author), Yu-yang Luo (Author), Da-yan Xiong (Author), Zi-qiang Luo (Author), Wei Liu (Author), Si-yuan Tang (Author)
• Format: Book
• Published: BMC, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Idiopathic pulmonary fibrosis is a persistent disease of the lung interstitium for which there is no efficacious pharmacological therapy. Protodioscin, a steroidal saponin, possesses diverse pharmacological properties; however, its function in pulmonary fibrosis is yet to be esta...