Cover Image

NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin

Abstract Background Idiopathic pulmonary fibrosis is a persistent disease of the lung interstitium for which there is no efficacious pharmacological therapy. Protodioscin, a steroidal saponin, possesses diverse pharmacological properties; however, its function in pulmonary fibrosis is yet to be esta...

Full description

Saved in:

Bibliographic Details
Main Authors:	Qian Zeng (Author), Bin-bin Wen (Author), Xin Liu (Author), Yong-yu Luo (Author), Zhen-gang Hu (Author), Lei Huang (Author), Xiao-hua Zhang (Author), Xiao-ting Huang (Author), Ting-ting Zhou (Author), Xiao-xue Sang (Author), Yu-yang Luo (Author), Da-yan Xiong (Author), Zi-qiang Luo (Author), Wei Liu (Author), Si-yuan Tang (Author)
Format:	Book
Published:	BMC, 2024-04-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin
by: Qian Zeng, et al.
Published: (2022)

Bicyclol Alleviates Signs of BDL-Induced Cholestasis by Regulating Bile Acids and Autophagy-Mediated HMGB1/p62/Nrf2 Pathway
by: Jingwen Zhao, et al.
Published: (2021)

Prevalence, characteristics and risk factors of birth defects in central China livebirths, 2015-2022
by: Ping Luo, et al.
Published: (2024)

Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis
by: Rui Chen, et al.
Published: (2022)

c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2
by: Min-Xia Su, et al.
Published: (2022)

Astragaloside IV alleviates 1-deoxysphinganine-induced mitochondrial dysfunction during the progression of chronic kidney disease through p62-Nrf2 antioxidant pathway
by: Ting Gui, et al.
Published: (2023)

Research Progress of Chinese Herbal Medicine Intervention in Renal Interstitial Fibrosis
by: Xiao-Yuan Liu, et al.
Published: (2022)

Genetic analysis of 62 Chinese families with Duchenne muscular dystrophy and strategies of prenatal diagnosis in a single center
by: Jingjing Zhang, et al.
Published: (2019)

STIMASI LUAS AREA TERBAKAR DENGAN METODE NORMALIZED BURN RATIO (NBR) (Studi Kasus : Provinsi Riau)
by: Niko Cendiana, -
Published: (2017)

Navigating therapeutic challenges in VEXAS syndrome: exploring IL-6 and JAK inhibitors at the forefront
by: Xiao Xiao Li, et al.
Published: (2024)

Sarmentosin alleviates doxorubicin-induced cardiotoxicity and ferroptosis via the p62-Keap1-Nrf2 pathway
by: Zhihui Lin, et al.
Published: (2024)

Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway
by: Ping Gao, et al.
Published: (2021)

Effect of zinc oxide on dispersion and homogeneity of PTFE in NR/NBR rubber matrices / Noorzalila Muhammad Niza and Buvearasan Muniandy
by: Muhammad Niza, Noorzalila, et al.
Published: (2015)

Research on the restorative effects and perception of privacy driven activities in Chinese classical gardens-Case studies of three Suzhou gardens
by: Hanxin Liu, et al.
Published: (2024)

Luteolin Exerts Neuroprotection via Modulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage
by: Xin Tan, et al.
Published: (2020)

Impact of maternal intrapartum antibiotics on the initial oral microbiome of neonates
by: Hongping Li, et al.
Published: (2019)

Is oral lichen planus a risk factor for peri-implant diseases? A systematic review and meta-analysis
by: Xiaoqin Xiong, et al.
Published: (2020)

Effect of breast milk with or without bacteria on infant gut microbiota
by: Ting Huang, et al.
Published: (2022)

Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion
by: Xin Chang, et al.
Published: (2023)

Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
by: Guiyun Wang, et al.
Published: (2024)

Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling
by: Mengyuan Wang, et al.
Published: (2023)

Involvement of the Nrf2 Pathway in the Regulation of Pterostilbene-Induced Apoptosis in HeLa Cells via ER Stress
by: Bo Zhang, et al.
Published: (2014)

Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling
by: Mengyuan Wang, et al.
Published: (2023)

Analysis of adverse drug reactions/events of cancer chemotherapy and the potential mechanism of Danggui Buxue decoction against bone marrow suppression induced by chemotherapy
by: Bin Yu, et al.
Published: (2023)

Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice
by: Fangze Huang, et al.
Published: (2023)

Mental health, sleep quality, and hormonal circadian rhythms in pregnant women with threatened preterm labor: a prospective observational study
by: Xiao-Juan Wang, et al.
Published: (2023)

Shenkang Injection and Its Three Anthraquinones Ameliorates Renal Fibrosis by Simultaneous Targeting IƙB/NF-ƙB and Keap1/Nrf2 Signaling Pathways
by: Liang-Pu Luo, et al.
Published: (2021)

Based on Activation of p62-Keap1-Nrf2 Pathway, Hesperidin Protects Arsenic-Trioxide-Induced Cardiotoxicity in Mice
by: Yuxin Jia, et al.
Published: (2021)

Folium Ginkgo extract and tetramethylpyrazine sodium chloride injection (Xingxiong injection) protects against focal cerebral ischaemia/reperfusion injury via activating the Akt/Nrf2 pathway and inhibiting NLRP3 inflammasome activation
by: Ting Zhu, et al.
Published: (2022)

Epidemiological characteristics and behaviors of online broadcast suicidality in China: implications for targeted prevention strategies
by: Chun-ya Li, et al.
Published: (2024)

Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells
by: Tsai TF, et al.
Published: (2020)

Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway
by: Liang Xiong, et al.
Published: (2022)

Mega-city construction engineering to residential satisfaction: new insights from Yan' an of China
by: Huan Huang, et al.
Published: (2023)

Hemoglobin concentrations in early pregnancy and their associations with adverse pregnancy outcomes in Western China: a population-based study
by: Li Tang, et al.
Published: (2024)

Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway
by: Qian Zeng, et al.
Published: (2024)

Structures of the SARS-CoV-2 spike glycoprotein and applications for novel drug development
by: Xiao-Huan Liu, et al.
Published: (2022)

Acute Kidney Injury Associated With Remdesivir: A Comprehensive Pharmacovigilance Analysis of COVID-19 Reports in FAERS
by: Bin Wu, et al.
Published: (2022)

Curcumin prevents As3+-induced carcinogenesis through regulation of GSK3β/Nrf2
by: Yuan-Ye Dang, et al.
Published: (2021)

Factors associated with workplace violence against Chinese healthcare workers: an online cross-sectional survey
by: Yu Xiao, et al.
Published: (2024)

The combination of Lonicerae Japonicae Flos and Forsythiae Fructus herb-pair alleviated inflammation in liver fibrosis
by: Jing-Bei Zhang, et al.
Published: (2022)