A novel TEX11 mutation induces azoospermia: a case report of infertile brothers and literature review

• Main Authors: Yanwei Sha (Author), Liangkai Zheng (Author), Zhiyong Ji (Author), Libin Mei (Author), Lu Ding (Author), Shaobin Lin (Author), Xu Wang (Author), Xiaoyu Yang (Author), Ping Li (Author)
• Format: Book
• Published: BMC, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Testis-expressed gene 11 (TEX11) is an X-linked gene and essential for meiotic recombination and chromosomal synapsis. TEX11 deficiency causes meiotic arrest and male infertility, and many TEX11 mutations have been found in azoospermic and infertile men. Case presentation This st...