Characterization of the cagA-gene in Helicobacter pylori in Mongolia and detection of two EPIYA-A enriched CagA types

• Main Authors: Oyunbaatar Altanbayar (Author), Avarzed Amgalanbaatar (Author), Chimeddorj Battogtokh (Author), Narmandakh Bayarjargal (Author), Dana Belick (Author), Malte Kohns Vasconcelos (Author), Colin R. Mackenzie (Author), Klaus Pfeffer (Author), Birgit Henrich (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Helicobacter pylori infection is strongly associated with gastritis, gastroduodenal ulcer disease and gastric carcinoma. The virulence of H. pylori strains increases with the presence of the pathogenicity island PAI, which encodes a Type 4 Secretion System and the oncoprotein CagA. Two major CagA ty...