FFAR1/GPR40 Contributes to the Regulation of Striatal Monoamine Releases and Facilitation of Cocaine-Induced Locomotor Activity in Mice

• Main Authors: Yuko Sadamura (Author), Shanta Thapa (Author), Ryota Mizunuma (Author), Yuki Kambe (Author), Akira Hirasawa (Author), Kazuo Nakamoto (Author), Shogo Tokuyama (Author), Koji Yoshimoto (Author), Kazunori Arita (Author), Atsuro Miyata (Author), Tatsuki Oyoshi (Author), Takashi Kurihara (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The free fatty acid receptor 1 (FFAR1) is suggested to function as a G protein-coupled receptor (GPR40) for medium-to-long-chain free fatty acids. Previous studies on the expression of FFAR1 revealed that the nigrostriatal region is one of the areas which express abundant FFAR1 mRNA/protein in the c...