Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs

• Główni autorzy: Khushboo Agrawal (Autor), Viswanath Das (Autor), Natálie Táborská (Autor), Ján Gurský (Autor), Petr Džubák (Autor), Marián Hajdúch (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2018-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The advanced-stage colon cancer spreads from primary tumor site to distant organs where the colon-unassociated stromal population provides a favorable niche for the growth of tumor cells. The heterocellular interactions between colon cancer cells and colon-unassociated fibroblasts at distant metasta...