Whole genome sequencing for drug resistance determination in Mycobacterium tuberculosis

• Main Authors: Shaheed V. Omar (Author), Lavania Joseph (Author), Halima M. Said (Author), Farzana Ismail (Author), Nabila Ismail (Author), Thabisile L. Gwala (Author), Nazir A. Ismail (Author)
• Format: Book
• Published: AOSIS, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

South Africa remains challenged with a high tuberculosis burden accompanied by an increase in drug resistant cases. We assessed the use of the Illumina MiSeq, a next-generation sequencing platform for whole genome sequencing, followed by bioinformatic analysis using a commercial software package to...