Lung Epithelial TRPA1 Transduces the Extracellular ROS into Transcriptional Regulation of Lung Inflammation Induced by Cigarette Smoke: The Role of Influxed Ca2+

The mechanism underlying the inflammatory role of TRPA1 in lung epithelial cells (LECs) remains unclear. Here, we show that cigarette smoke extract (CSE) sequentially induced several events in LECs. The Ca2+ influx was prevented by decreasing extracellular reactive oxygen species (ROS) with the scav...

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Main Authors: An-Hsuan Lin (Author), Meng-Han Liu (Author), Hsin-Kuo Ko (Author), Diahn-Warng Perng (Author), Tzong-Shyuan Lee (Author), Yu Ru Kou (Author)
Format: Book
Published: Hindawi Limited, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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