Curcumin, Polydatin and Quercetin Synergistic Activity Protects from High-Glucose-Induced Inflammation and Oxidative Stress

• Main Authors: Giulia Matacchione (Author), Debora Valli (Author), Andrea Silvestrini (Author), Angelica Giuliani (Author), Jacopo Sabbatinelli (Author), Chiara Giordani (Author), Sofia Coppari (Author), Maria Rita Rippo (Author), Maria Cristina Albertini (Author), Fabiola Olivieri (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic hyperglycemia, the diagnostic biomarker of Type 2 Diabetes Mellitus (T2DM), is a condition that fosters oxidative stress and proinflammatory signals, both involved in the promotion of cellular senescence. Senescent cells acquire a proinflammatory secretory phenotype, called SASP, exacerbatin...