Intranasal vaccination with leishmanial antigens protects golden hamsters (Mesocricetus auratus) against Leishmania (Viannia) Braziliensis infection.

• Main Authors: Luzinei da Silva-Couto (Author), Raquel Peralva Ribeiro-Romão (Author), Andrea Franco Saavedra (Author), Beatriz Lilian da Silva Costa Souza (Author), Otacílio Cruz Moreira (Author), Adriano Gomes-Silva (Author), Bartira Rossi-Bergmann (Author), Alda Maria Da-Cruz (Author), Eduardo Fonseca Pinto (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previous results have shown that oral and intranasal administration of particulate Leishmania (Leishmania) amazonensis antigens (LaAg) partially protects mice against L. amazonensis infection. However, vaccination studies on species of the subgenus Viannia, the main causative agent of cutaneous and...