A Novel Cross-Linked Hemoglobin-Based Oxygen Carrier, YQ23, Extended the Golden Hour for Uncontrolled Hemorrhagic Shock in Rats and Miniature Pigs

• Main Authors: Lei Kuang (Author), Yu Zhu (Author), Yue Wu (Author), Kunlun Tian (Author), Xiaoyong Peng (Author), Mingying Xue (Author), Xinming Xiang (Author), Billy Lau (Author), Fei Chuen Tzang (Author), Liangming Liu (Author), Tao Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hypotensive resuscitation is widely applied for trauma and war injury to reduce bleeding during damage-control resuscitation, but the treatment time window is limited in order to avoid hypoxia-associated organ injury. Whether a novel hemoglobin-based oxygen carrier (HBOC), YQ23 in this s...