Neuroprotective activity of a virus‐safe nanofiltered human platelet lysate depleted of extracellular vesicles in Parkinson's disease and traumatic brain injury models

• Main Authors: Liling Delila (Author), Ouada Nebie (Author), Nhi Thao Ngoc Le (Author), Lassina Barro (Author), Ming‐Li Chou (Author), Yu‐Wen Wu (Author), Naoto Watanabe (Author), Masayasu Takahara (Author), Luc Buée (Author), David Blum (Author), David Devos (Author), Thierry Burnouf (Author)
• Format: Book
• Published: Wiley, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Brain administration of human platelet lysates (HPL) is a potential emerging biotherapy of neurodegenerative and traumatic diseases of the central nervous system. HPLs being prepared from pooled platelet concentrates, thereby increasing viral risks, manufacturing processes should incorporat...