Escinosomes: Safe and Successful Nanovesicles to Deliver Andrographolide by a Subcutaneous Route in a Mice Model of Oxaliplatin-Induced Neuropathy

• Main Authors: Giulia Vanti (Author), Michela Capizzi (Author), Lorenzo Di Cesare Mannelli (Author), Elena Lucarini (Author), Maria Camilla Bergonzi (Author), Carla Ghelardini (Author), Anna Rita Bilia (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Andrographolide (AG) is a natural diterpene lactone endowed with considerable therapeutic potential for treating numerous diseases, including neurological disorders, but its low aqueous solubility and scarce bioavailability limit its clinical use. To overcome this problem, AG was encapsulated in esc...