Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling

• Main Authors: Rebecca C. Schugar (Author), Ashley R. Moll (Author), D. André d'Avignon (Author), Carla J. Weinheimer (Author), Attila Kovacs (Author), Peter A. Crawford (Author)
• Format: Book
• Published: Elsevier, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Exploitation of protective metabolic pathways within injured myocardium still remains an unclarified therapeutic target in heart disease. Moreover, while the roles of altered fatty acid and glucose metabolism in the failing heart have been explored, the influence of highly dynamic and nut...