BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux

• Main Authors: Shuangjun Shen (Author), Bin Li (Author), Juanjuan Dai (Author), Zengkai Wu (Author), Yan He (Author), Li Wen (Author), Xingpeng Wang (Author), Guoyong Hu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Impaired autophagy has been shown to play a critical role in experimental and human acute pancreatitis (AP). However, the mechanism for transcriptional regulation of autophagy remains largely unknown. In this study, we aim to explore the role of BRD4 (bromodomain-containing protein 4), a transcripti...