Recombinant truncated latency-associated peptide alleviates liver fibrosis in vitro and in vivo via inhibition of TGF-β/Smad pathway

• Main Authors: Xudong Song (Author), Jiayi Shi (Author), Jieting Liu (Author), Yong Liu (Author), Yang Yu (Author), Yufei Qiu (Author), Zhiqin Cao (Author), Yu Pan (Author), Xiaohuan Yuan (Author), Yanhui Chu (Author), Dan Wu (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Liver fibrosis is a progressive liver injury response. Transforming growth factor β1 (TGF-β1) is oversecreted during liver fibrosis and promotes the development of liver fibrosis. Therapeutic approaches targeting TGF-β1 and its downstream pathways are essential to inhibit liver f...