Tanshinone IIA Inhibits the Endoplasmic Reticulum Stress-Induced Unfolded Protein Response by Activating the PPARα/FGF21 Axis to Ameliorate Nonalcoholic Steatohepatitis

• Main Authors: Dajin Pi (Author), Zheng Liang (Author), Jinyue Pan (Author), Jianwei Zhen (Author), Chuiyang Zheng (Author), Wen Fan (Author), Qingliang Song (Author), Maoxing Pan (Author), Qinhe Yang (Author), Yupei Zhang (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic steatohepatitis (NASH) is a critical stage in the progression of nonalcoholic fatty liver disease (NAFLD). Tanshinone IIA (TIIA) is a tanshinone extracted from Salvia miltiorrhiza; due to its powerful anti-inflammatory and antioxidant biological activities, it is commonly used for treat...