Cancer stem cell-targeted chimeric antigen receptor (CAR)-T cell therapy: Challenges and prospects

• Main Authors: Javad Masoumi (Author), Abdollah Jafarzadeh (Author), Jalal Abdolalizadeh (Author), Haroon Khan (Author), Jeandet Philippe (Author), Hamed Mirzaei (Author), Hamid Reza Mirzaei (Author)
• Format: Book
• Published: Elsevier, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer stem cells (CSCs) with their self-renewal ability are accepted as cells which initiate tumors. CSCs are regarded as interesting targets for novel anticancer therapeutic agents because of their association with tumor recurrence and resistance to conventional therapies, including radiotherapy a...