Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity.

Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity.

Trans-sialidases (TS) represent a multi-gene family of unusual enzymes, which catalyse the transfer of terminal sialic acids (Sia) from sialoglycoconjugates to terminal galactose or N-acetylgalactosamine residues of oligosaccharides without the requirement of CMP-Neu5Ac, the activated Sia used by ty...

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Main Authors: Mario Waespy (Author), Thaddeus Termulun Gbem (Author), Nilima Dinesh Kumar (Author), Shanmugam Solaiyappan Mani (Author), Jana Rosenau (Author), Frank Dietz (Author), Sørge Kelm (Author)
Format: Book
Published: Public Library of Science (PLoS), 2022-02-01T00:00:00Z.
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