2,3,5,4'-Tetrahydroxy-stilbene-2-O-beta-d-glucoside induces autophagy-mediated apoptosis in hepatocytes by upregulating miR-122 and inhibiting the PI3K/Akt/mTOR pathway: implications for its hepatotoxicity

• Main Authors: Lei Yang (Author), Wei Xing (Author), Wang-Zhong Xiao (Author), Lin Tang (Author), Lu Wang (Author), Meng-Jiao Liu (Author), Bing Dai (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context The potential hepatotoxicity of Polygoni Multiflori Radix (PMR) has attracted much attention, but the specific mechanism of inducing hepatotoxicity is still unclear due to the complexity of its components. Objective This study investigated the specific mechanism by which 2,3,5,4'-tetrah...